Clinical trial recruitment platforms

A familiar challenge in clinical trials

Clinical trial teams often inherit digital setups that were never designed for the realities of research delivery. Common challenges include:

Managing participant recruitment across multiple sites
Handling informed consent and re-consent as trials evolve
Coordinating appointments, hubs, and trial locations
Collecting and separating sensitive data appropriately
Adapting processes as protocols change mid-trial

These are normal features of running real trials and they require systems that can accommodate change without introducing risk. This is the environment we design for.

Ethics and governance shape the platform

Clinical trials operate within strict ethical and governance frameworks and digital systems must respect that context. We design platforms where ethical considerations are embedded from the start, including:

Consent processes that are clear, traceable, and adaptable.

Auditability of participant and admin user interactions.

Appropriate separation of identifiable and anonymised data.

Role-based access aligned with responsibility and clearance.

A stable foundation, adapted to each trial

While every trial is different, many of the underlying requirements repeat.

We work from a stable, proven platform foundation that is adapted and configured to fit the specific needs of each trial which is informed by the protocol, governance requirements, and operational realities.

This approach allows teams to benefit from prior learning and robustness, while still receiving a system that is appropriate to their trial rather than a generic template.

Stability and flexibility are treated as complementary, not competing, goals.

Clinical trials we’ve worked on

We’re extremely proud of our work with various clinical trials units, having worked on five separate trials with different providers and university teams. We continue to seek opportunities within this important area to help improve patient recruitment, safety, and trial management.

SAFE-D

Our latest work on the SAFE-D study will evaluate the Avantect novel blood test, to detect biomarkers for the presence of early-stage pancreatic cancer. Now in Phase 1, the recruitment and appointment booking engine we developed has led to 477 recruited patients on behalf of US healthcare provider, ClearNote.

EXCALIBUR

A Phase 3 feasibility trial which investigated whether the Chinese herbal medicine Shufeng Jiedu could help reduce antibiotic use during acute episodes of COPD. Our platform helped recruit patients through prescreening, informed consent and randomisation of patient data.

CADET

CaDeT was a randomised trial which aimed to determine whether an alternative catheter design could prove clinically safer and more cost-effective treatment to long-term patients. Our platform helped recruit patients, accept informed consent digitally and helped patient management.

SG016 Covid Trial at Home

In collaboration with Synairgen Plc, the SG016 trial was a phase 2, randomised, double-blind, placebo-controlled study that investigated the safety and efficacy of inhaled SNG001 for the treatment of patients with confirmed COVID-19. Our trials platform led in the recruitment of 120 patients.

AGILE

AGILE is a multicentre, multi-arm, multi-dose, multi-stage open-label, adaptive, seamless phase I/II Bayesian randomised platform trial to determine the optimal dose, activity and safety of multiple candidate agents for the treatment of COVID-19.

What our platforms typically support

Clinical trial platforms are shaped around operational needs, not feature lists. Depending on the trial, this may include:

participant registration and eligibility pre-screening
informed consent and re-consent workflows
appointment booking and visit coordination
management of trial sites, hubs, and locations
separation and handling of sensitive and anonymised data
administrative oversight and reporting for trial teams
integration with 3rd party systems

These capabilities are implemented proportionately, based on what each trial protocol requires.

Supporting trial teams through setup and change

We understand that trial teams are focused on delivery, not learning new software. Our role includes guiding teams through setup and change, including:

Configuring the platform around the trial protocol
Supporting ethics-led workflows such as consent and re-consent
Helping teams adapt the system as trials evolve
Ensuring administrators understand how to use the platform confidently

Testimonials

From the outset, it was clear that we were fortunate to work with a team that not only possessed the technical expertise but also listened and shared our vision and commitment to excellence.

Dr. Adeniyi Olagunju

Senior Lecturer, University of Liverpool

When 10 Degrees delivered our SAFE-D project, the entire Southampton CTU team wished we had another project we could immediately start working on with them! The post-go live support has proven to be as responsive, creative and competent as the design and development side of their business.

Angelica Cazaly

Trial Manager, Southampton CTU

Jonny and the 10 Degrees team have done a fantastic job in designing and implementing the SG016 trial website to our tight study opening deadline. The level of functionality available has exceeded our expectations and allows us to maintain and manage patient recruitment with ease.

Tom Oliver

Trial Manager, Southampton CTU

Frequently asked questions

Are your clinical trial platforms suitable for regulated research environments?

Yes. Platforms are designed with ethics, governance, and auditability in mind, and are adapted to fit the requirements of individual trials and research contexts.

How do you support informed consent and re-consent?

We design clear, traceable consent workflows that can accommodate changes to trial protocols, including re-consent where required, with appropriate oversight and audit trails.

Can platforms support multi-site or hub-based trials?

Yes. Platforms can support multiple trial sites or hubs, with appropriate permissions and workflows for appointments, visits, and coordination across locations.

How is sensitive participant data handled?

Systems are designed to separate identifiable and anonymised data appropriately, with role-based access aligned to responsibility and governance requirements.

Is each clinical trial platform bespoke?

Yes. We support trial teams as platforms evolve, including changes to workflows, consent requirements, or operational processes during the life of a trial.

Do you support platforms after a trial has launched?